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MS may offer distinct advantages compared with MT in treating chronic heart failure patients with beta-adrenergic blocking agents.

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Poor metabolizers and extensive metabolizers who concomitantly use CYP2D6 inhibiting drugs will have increased (several-fold) metoprolol blood levels, decreasing metoprolol's cardioselectivity.

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Tomorrow will try again the Metoprolol and adjust my dose with higher dose in the morning and lower dose for the rest of the day and 4 doses, not 2 doses like the Cardio Doc say.

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